What is Yessum?

A response usually used alone in a mumbling manor to tell people that you are paying attention to them and you understand.

Jill: Can we go up the hill?

Jack: Yessums

Yessum - meme gif

When you say yessums, you mean "yes"

How Cole Hutto answers his phone

"Yes ma'am," common southern slang. It's a term of respect to a woman, usually older than the speaker.

"Go kill yourself, you stupid fuck."
"...yessum..."

an affirmative answer of a yes/no question; originating in Southern US shortened version of "yes, ma'am"

yessum, miss daisy i'll drive you to the store, yessum.

From 1920's america, was used in the deep south by Jem and Scout in the book "To kill a Mocking Bird" means yes

Nicole - "Have you seen my boots"
Jessica - "Yessum, they're by the door"

Sorta like "yes ma'am" only spoken very fast.

Shave your balls, that tea-bagging session we had last night nearly clogged my throat with hair like a shower drain.
Yessum.

Southern polite people say "Yessum" to a female(usually an elder) meaning "Yes Ma'am". Can also be spelled "Yes'm"

Teacher: Warsh the chalk board and then you can go home.
Student: Yessum.