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What is powder your nose?
Slang for snorting cocaine (or any other drug).
Bill: This club is great, but lets go to the bathroom for a sec.
Lisa: What for? U think I'm gonna fuck you or something?
Bill: I'm gonna be powdering your nose. U wanna try it?
Lisa: I could do a few lines.
Bill: Cool. Keep it on the DL, let's go
powder your nose - video
Powder your nose - what is it?
Snorting cocaine in the bathroom
Guy: How long has it been since you went to powder your nose?
Bob: Quite some time now