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What is weekend immune system?
Hungover/dead in various parts of body
Weekend immune system got me dead
weekend immune system - video
Weekend immune system - what is it?
Another way of saying drunk and/or hungover. Owing to alcohols ability to suppress the immune system and the fact that it is usually drunk in largest quantities on the weekend.
Ugh yeah I'm not going to be able to come in to work today, I have a weekend immune system