What is panties in your mouth?

—used as a generalized term of approval or congratulations.

: markedly superior in character or quality.

: marvelous, astonishing.

: unusually good, admirable.

Dude 1: Dude, I just a got a promotion and a sweet beej from my new secretary.

Dude 2: Dude, panties in your mouth! (followed by a leaping high-five)

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panties in your mouth - video