What is hasta la polla?

It's a Spanish expression that defines tiredness about something or can't handle it anymore.

When you are 'hasta la polla' you feel like you can not keep doing something or being in a specific situation anymore. Similar to 'sick of'
A literal translation would be 'up to the dick', so if you are tired of your uni exams you could say: 'I'm up to the dick of my exams'