What is chrissake?

A shorthand version of "for Christ's sake."

Chrissakes Katie, tuck your black thong back into your pants. Your mom is here.

chrissake - meme gif

Interjection used to express great astonishment, shock or similar feelings. Contraction of "christ sake". Similar to omigod

For chrissake, did Jack really do that?
Yup, straight up the A!