What is You must have Ebola?

This is a very famous quote from UgandanKnucles (Ugandan Knuckles) who wants to find DaWae(Da Wae)

Ugandan Knuckles: Do you knoe da wae to da queen? (DaQueen)
Hater: Nu
Ugandan Knuckles: .o. You must have Ebola

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You must have Ebola - video