Definder - what does the word mean?

What is Que Isso?

Brazilian phrase meaning WTF (what the fuck)

Also, famous song by brazilian funk artist MC Saed - Que Isso Novinha.

Flavia: this water tastes very good. I wonder what flavor is it???
Marcelo: i pissed in the bottle last night after drinking too much!
Flavia: Puta que pariu! Que Isso marcelo, que isso!

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Que Isso - video

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