Definder - what does the word mean?

What is touch o' downs?

A symptom exhibited by an individual who has the appearance of partial Down Syndrome but does not appear to have any of the characteristics.

Hector (whispers to his friend, Paul, referring to passerby): Damn! Check out that fucked up dude with the fivehead.

Paul: Man that's fucked up. He probably got a "touch o' downs".

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touch o' downs - video

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