Definder - what does the word mean?

What is tolerance break?

A phrase used mainly by weed smokers. It refers to taking a break from smoking, or smoking less often, in an attempt to lower your tolerance to THC, and thus gain a better high each time you do smoke.

Yo man, I've been blazing up every day for a month, and it's just not the same anymore. I need to take a tolerance break.

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tolerance break - video