What is take your pills?

An expression of speech used in retort to someone who is behaving like a lunatic. Implies that the individual depends on medicine to function, and that his/her erratic behavior can be attributed to missing a dose of said medicine.

Person 1: 'Good morning'

Person 2: 'WHATS SO FUCKING GOOD ABOUT IT ASSHOLE?!!!'

Person 1: 'Take your pills man, holy shit'

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take your pills - video