What is sisterfucker?

A husband or boyfriend that has female best friend that he says "she is like a sister to me". When in reality, he is cheating and is actually fucking the female friend.

John-doe is a lying Sisterfucker.

sisterfucker - video

Sisterfucker - what is it?

The male residents of Alabama

Sisterfucker. S-I-S-D-U-uh....-D-E-uh...R...fucker. Sisterfucker.
-Alabamian