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What is nic'd up?
A phrase said after consuming a high dose of nicotine, usually by vaping, causing one to feel a strong buzz. This can lead to the user feeling sick, possibly from nicotine poisoning. However, in most cases a quick rest and some water will cure any ill feelings.
Guy: "Alright bro you ready to head out?"
Bro: "Let me lay down for about 5 minutes, I just took a few fat hits off the Juul and now I'm nic'd up."
nic'd up - video
Nic'd up - what is it?
Using enough nicotine to make you feel intoxicated
"You tryna smoke a cig?"
"Nah man I'm nic'd up"