1. Mesembrine is an alkaloid present in Sceletium tortuosum. 2. It has been shown to be an extremely potent serotonin reuptake inhibitor, active at dosages as low as 100956;g (micrograms). 3. It has also been shown to be a PDE4-inhibitor.3 Mesembrine may contribute to the antidepressant effects of kanna.
Wow, this kanna sure does seem like it is loaded with Mesembrine!
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