Definder - what does the word mean?

What is deeez nuuuts?

An interjection often used after one of the five W's (who, what, where, when, why). A humourous statement, it stems from the Dr. Dre song of the same name.

Dre: Did whatsername get out to you yesterday?
Bitch: Who?
Dre: Deeez Nuuuts!

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deeez nuuuts - video