Definder - what does the word mean?

What is You couldn't catch herpes in a whorehouse?

A more sexually explicit version of, "You couldn't catch a cold", meaning that someone is not good at catching anything.

Wally was so non-athletic, he couldn't catch herpes in a whorehouse.

OR

Being pursued by bad guys: Can't you guys keep up? You couldn't catch herpes in a whorehouse!

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You couldn't catch herpes in a whorehouse - video