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What is Jamie Lee Curtis?
To take a dump; to crap; to empty ones bowels. Especially after eating a large serving of Activia brand yogurt.
"Oh God, my stomach hurts! I need to go to the bathroom and take a huge Jamie Lee Curtis."
"Honey, we have to change the baby's diaper. He Jamie Lee Curtissed, again."
"You look constipated. Perhaps you need to take a Jamie Lee Curtis."